How to Pronounce Loss of Self-Tolerance
Definition, meaning, and phonetic spelling
Loss of Self-Tolerance Pronunciation
loss of self TOL-er-ants
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
loss of self TOL
er
ants
3 syllables
What is Loss of Self-Tolerance?
The breakdown of the normal immune mechanisms that prevent the immune system from attacking the body's own tissues; it is the fundamental underlying event in all autoimmune diseases and can result from genetic predisposition, environmental triggers, and dysregulation of immune checkpoints.
Questions About Loss of Self-Tolerance
How do you pronounce 'loss of self-tolerance'?
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Say it like this: 'loss of self TOL-er-ants.' The stress falls on the first syllable of 'tolerance'—that's the TOL part. It's pronounced the same way you'd say 'tolerate' in everyday speech, just with '-ance' at the end instead of '-ate.'
What is the stressed syllable in 'loss of self-tolerance'?
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The stressed syllable is TOL in the word 'tolerance.' A common mistake is stressing the second syllable—er—but the emphasis should come on the first part: TOL-er-ants, not tol-ER-ants.
How do you break 'loss of self-tolerance' into syllables?
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Break it down like this: 'loss' (one syllable) + 'of' (one syllable) + 'self' (one syllable) + 'tol-er-ance' (three syllables). So the whole phrase is seven syllables: loss of self TOL-er-ants.
What does 'self-tolerance' mean in plain English?
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In plain English, self-tolerance means your body's ability to recognize its own tissues and leave them alone instead of attacking them. When you lose it, your immune system gets confused and starts treating your own body as if it were a harmful invader.
Where does the word 'tolerance' come from?
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The word 'tolerance' comes from the Latin word 'tolerantia,' which means 'the ability to bear or endure.' In medical language, it specifically means your body's ability to accept or allow something without attacking it.
What related medical words share the root 'tol-' from 'tolerance'?
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Other medical words with the same root include 'drug tolerance' (when a medicine stops working as well), 'immune tolerance' (when your body accepts a foreign substance), and 'tolerate' (to allow something without a harmful reaction).
How would you use 'loss of self-tolerance' correctly in a sentence?
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Here's an example: 'Loss of self-tolerance is the key problem that happens in autoimmune diseases.' This sentence correctly describes what the term means without giving medical advice.
Why is 'self-tolerance' an important medical term to understand?
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Understanding this term helps you grasp how doctors talk about autoimmune conditions, which are diseases where the body's defenses turn against it. Knowing what 'loss of self-tolerance' means makes it easier to follow medical conversations and read health information.