How to Pronounce Citrullinemia
Definition, meaning, and phonetic spelling
Citrullinemia Pronunciation
sih-trul-ih-NEE-mee-ah
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
sih
trul
ih
NEE
stress here
mee
ah
6 syllables
What is Citrullinemia?
A urea cycle disorder caused by deficiency of argininosuccinate synthetase, causing accumulation of citrulline and ammonia in the blood and leading to hyperammonemia. The severe neonatal form causes rapidly progressive brain damage if untreated.
Questions About Citrullinemia
How do you pronounce citrullinemia?
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Citrullinemia is pronounced sih-TRUL-ih-NEE-mee-ah. The stress falls on the second syllable (TRUL), which should sound like the word "truly" without the "y" at the end. Say it slowly at first: sih-TRUL-ih-NEE-mee-ah, then speed it up once you're comfortable.
What is the correct way to break citrullinemia into syllables?
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Citrullinemia breaks into six syllables: cit-rul-li-ne-mi-a. If you sound out each part separately—cit (like "sit"), rul, li, ne (like "knee"), mi, a—it becomes much easier to pronounce the full word.
Which syllable do people stress incorrectly in citrullinemia?
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Many people incorrectly stress the first syllable and say "SIH-trul-ih-nee-mee-ah," but the correct stress is on the second syllable: sih-TRUL-ih-nee-mee-ah. Remember to put the emphasis on "TRUL" to say it right.
What does the word root 'citrulline' refer to, and where does it come from?
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Citrulline comes from the Latin word "citrullus," which means watermelon. The amino acid was named this way because it was first discovered in watermelon juice. The suffix "-emia" means "in the blood," so citrullinemia literally means "citrulline in the blood."
What does '-emia' mean in citrullinemia?
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The suffix "-emia" is a medical term meaning "condition of the blood" or "substance present in the blood." When you see "-emia" at the end of a medical word, it tells you the word is describing something abnormal found in someone's blood.
What is the plain English meaning of citrullinemia?
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Citrullinemia simply means there is too much of a chemical called citrulline in the blood. It's a medical condition where a certain substance builds up to harmful levels, but understanding the word just requires knowing it refers to a blood-related condition.
What are some related medical words that use the same '-emia' ending?
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Many medical conditions use the "-emia" ending to describe blood problems. You may hear words like "anemia" (low red blood cells), "hyperglycemia" (high blood sugar), or "hypercalcemia" (high blood calcium). All of these follow the same pattern of naming a condition based on what's abnormal in the blood.
Can you use citrullinemia in a simple sentence?
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Here's an example: "The doctor explained that the test results showed citrullinemia, which is why they need to do further testing." This sentence shows how you might hear the word used in a medical conversation without any health advice attached.

