How to Pronounce Aspirin-Exacerbated Respiratory Disease
Definition, meaning, and phonetic spelling
Aspirin-Exacerbated Respiratory Disease Pronunciation
AS-pih-rin eg-ZAS-er-bay-ted res-PIR-ah-tor-ee dih-ZEEZ
Stressed syllable in ALL CAPS · hyphens separate syllables
Syllable Breakdown
AS
stress here
pih
rin eg
ZAS
stress here
er
bay
ted res
PIR
stress here
ah
tor
ee dih
ZEEZ
stress here
12 syllables
What is Aspirin-Exacerbated Respiratory Disease?
Also called Samter's triad or NSAID-exacerbated respiratory disease, this is a syndrome comprising asthma, chronic rhinosinusitis with nasal polyps, and sensitivity to aspirin and NSAIDs; it is caused by dysregulated arachidonic acid metabolism and represents an immune-inflammatory condition.
Questions About Aspirin-Exacerbated Respiratory Disease
How do you pronounce 'Aspirin-Exacerbated Respiratory Disease'?
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Say it like this: AS-pih-rin eg-ZAS-er-bay-ted res-PIR-ah-tor-ee dih-ZEEZ. The stress falls on the first syllable of each main word: AS (in aspirin), ZAS (in exacerbated), PIR (in respiratory), and ZEEZ (in disease). It's a long term, so take it one word at a time and it becomes easier.
What part of the term gets the strongest stress?
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The strongest stress falls on AS at the very beginning—AS-pih-rin. A common mistake is putting equal weight on all the words or stressing the middle part (exacerbated). Remember to punch the first syllable and let the rest flow more lightly.
How do you break this term into syllables?
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Break it into four main word chunks: As-pir-in (3 syllables) / Ex-as-cer-bat-ed (5 syllables) / Res-pir-a-tor-y (5 syllables) / Dis-ease (2 syllables). Saying each word separately first helps you put them together smoothly.
What do the word parts mean?
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Aspirin is a common pain reliever. Exacerbated means 'made worse.' Respiratory relates to breathing and the lungs. Disease means an illness or health condition. So the whole phrase describes a breathing-related condition that gets worse when exposed to aspirin.
What is another name for this condition?
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It's also called Samter's triad (SAM-terz TRY-ad) or NSAID-exacerbated respiratory disease. All three names refer to the same condition, so you might hear any of them in medical conversations. NSAID stands for nonsteroidal anti-inflammatory drug.
What does 'exacerbated' mean in plain English?
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Exacerbated (eg-ZAS-er-bay-ted) simply means 'made worse' or 'made more severe.' When something exacerbates a problem, it causes it to become worse, not better. In this term, it describes how aspirin and similar drugs make the respiratory condition more serious.
How would you use this term in a sentence?
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You might hear: 'The patient was diagnosed with Aspirin-Exacerbated Respiratory Disease, so the doctor discussed which pain relievers would be safe for them.' Or: 'Aspirin-Exacerbated Respiratory Disease combines breathing problems with sensitivity to certain medications.'
What is the short form or abbreviation?
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The abbreviation is AERD (pronounced letter-by-letter: A-E-R-D). You'll often see doctors use AERD in written notes because it's faster to write and say than the full term. NERD (NSAID-Exacerbated Respiratory Disease) is another abbreviation you might encounter.

